![]() High SEC62 expression levels were observed in various cancer entities and were associated with a poor outcome and increased metastatic burden. Located in the ER membrane, this translocation protein is known to play a critical role as a potential driver oncogene in cancer development. Various cancer types including head and neck squamous cell carcinomas (HNSCC) show a frequent amplification of chromosomal region 3q26 that encodes, among others, for the SEC62 gene. ![]() 3Institute for Clinical and Experimental Surgery, Saarland University, Homburg, Germany.2Experimental and Clinical Pharmacology and Toxicology, Pre-Clinical Center for Molecular Signalling (PSMZ), Saarland University, Homburg, Germany. ![]() 1Department of Otorhinolaryngology, Head and Neck Surgery, Saarland University Medical Center, Homburg, Germany.Menger 3, Adolfo Cavalié 2, Jan-Philipp Kühn 1, Bernhard Schick 1 and Maximilian Linxweiler 1* ![]() Sandrina Körner 1, Tillman Pick 2, Florian Bochen 1, Silke Wemmert 1, Christina Körbel 3, Michael D. ![]()
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